Breeders should inform prospective owners of conditions where DNA tests are currently in place and breed only from animals that are tested negative, or are negative by descent for the PHPT gene.
Some good news from the newly opened Kennel Club Genetics Centre (KCGC) to say that they are settling into the Department of Veterinary Medicine at the University of Cambridge and the team, led by Dr Cathryn Mellersh, now has a full complement of 9 members, all of whom have come from the Animal Health Trust
The past few weeks have been spent sorting out their new space, unpacking samples, downloading data and finding their way around. As a result of the pandemic they are still largely working from home which has meant the moving in process has taken a bit longer than it would done under normal circumstances, but are more or less ‘back to business’ now.
They now have a brand new, recently launched website at www.canine-genetics.org.uk. where they list their current research areas as : Inherited Eye Diseases – such as Glaucoma, Progressive Retinal Atrophy (PRA), Primary Lens Luxation (PLL) etc. Neurological Disorders – such as Idiopathic Epilepsy & Paroxysmal Dyskinesia. Congenital hepatic fibrosis in Skye Terriers and last but not least - Primary Hyperparathyroidism (PHPT) in Keeshonds.
This is the news that we have all been waiting for and hopefully the linkage test for PHPT will be made available just a little later than originally planned!
Below is a link to the UK Kennel Club's list of all Keeshonds registered (or appearing in a UK pedigree) in the UK who have been PHPT tested.
Tom Lewis: "It is demonstrated in this study that, when ‘hereditary clear’ status is repeatedly assigned over a number of generations, a modest rate of false paternity can result in a notable proportion of ‘hereditary clear’ assignments being false, unless the disease causing mutation frequency is very low."
"In light of these findings and to reduce the risks of producing puppies destined to be affected by such diseases, the Kennel Club has determined to limit the assignment of ‘hereditary clear’ status of registered dogs to 2 generations, with effect from January 2022."